This may sound like a contradiction, but a business degree really isn't necessary to run a business. Despite all the well-meaning parents out there who strongly recommend it, entrepreneurs are not "cookie cutter" business majors.
If business ownership is your aspiration, it never hurts to have an education, but a true entrepreneur makes his or her own destiny. You will rarely need an impressive-looking resume; and for that matter you really don't need a degree at all. Believe it or not, one of the best things college can do is teach you discipline. You might also meet some valuable business connections while you're there.